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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ITPKA
All Species:
35.76
Human Site:
Y270
Identified Species:
78.67
UniProt:
P23677
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P23677
NP_002211.1
461
51009
Y270
C
K
M
G
V
R
T
Y
L
E
E
E
L
T
K
Chimpanzee
Pan troglodytes
XP_001149577
401
45057
Y210
C
K
M
G
V
R
T
Y
L
E
E
E
L
T
K
Rhesus Macaque
Macaca mulatta
XP_001099176
645
70639
Y454
C
K
M
S
V
R
T
Y
L
E
E
E
L
T
K
Dog
Lupus familis
XP_544631
632
69191
Y441
C
K
M
G
V
R
T
Y
L
E
E
E
L
T
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8R071
459
50916
Y268
C
K
M
G
V
R
T
Y
L
E
E
E
L
T
K
Rat
Rattus norvegicus
P17105
459
50852
Y268
C
K
M
G
V
R
T
Y
L
E
E
E
L
T
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_990212
452
51079
Y261
C
K
M
G
I
R
T
Y
L
E
E
E
L
T
K
Frog
Xenopus laevis
NP_001088157
516
58252
Y325
C
K
M
G
V
R
T
Y
L
E
E
E
L
V
K
Zebra Danio
Brachydanio rerio
Q5TZ07
288
31266
D119
L
G
V
C
A
C
E
D
S
S
W
G
S
V
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572875
669
73198
Y444
C
K
V
G
V
R
T
Y
L
E
E
E
L
S
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795627
356
40840
D187
Y
Q
K
M
I
E
I
D
P
N
A
P
T
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.5
70.5
68.6
N.A.
93.2
93.4
N.A.
N.A.
64.6
44.5
21
N.A.
37.6
N.A.
N.A.
42.7
Protein Similarity:
100
86.5
70.8
69.7
N.A.
96
96
N.A.
N.A.
74.6
57.9
32.9
N.A.
46.6
N.A.
N.A.
53.8
P-Site Identity:
100
100
93.3
100
N.A.
100
100
N.A.
N.A.
93.3
93.3
0
N.A.
86.6
N.A.
N.A.
0
P-Site Similarity:
100
100
93.3
100
N.A.
100
100
N.A.
N.A.
100
93.3
13.3
N.A.
100
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
0
0
0
0
10
0
0
0
0
% A
% Cys:
82
0
0
10
0
10
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
19
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
10
10
0
0
82
82
82
0
10
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
73
0
0
0
0
0
0
0
10
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
19
0
10
0
0
0
0
0
0
0
0
% I
% Lys:
0
82
10
0
0
0
0
0
0
0
0
0
0
0
82
% K
% Leu:
10
0
0
0
0
0
0
0
82
0
0
0
82
0
0
% L
% Met:
0
0
73
10
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
10
0
0
10
0
0
0
% P
% Gln:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
82
0
0
0
0
0
0
0
0
10
% R
% Ser:
0
0
0
10
0
0
0
0
10
10
0
0
10
10
0
% S
% Thr:
0
0
0
0
0
0
82
0
0
0
0
0
10
64
0
% T
% Val:
0
0
19
0
73
0
0
0
0
0
0
0
0
19
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
82
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _